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Assessing eligibility for lung cancer screening using parsimonious ensemble machine learning models: A development and validation study

Authors: Thomas Callender , et al. Abstract Background Risk-based screening for lung cancer is currently being considered in several countries; however, the optimal approach to determine eligibility remains unclear. Ensemble machine learning could support the development of highly parsimonious prediction models that maintain the performance of more complex models while maximising simplicity and generalisability, supporting…

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Value of a catch-up HPV test in women aged 65 and above: A Danish population-based nonrandomized intervention study

Authors: Mette Tranberg , et al. Study population From a total of 45,237 women eligible, 11,369 and 33,868 were allocated to the intervention and reference groups, respectively (Fig 1). After exclusions during follow-up, 11,192 (98.4%) women in the intervention group and 33,387 women (98.6%) in the reference group were included for analysis (Fig 1). The…

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Cervical cancer screening utilization and associated factors among female health workers in public health facilities of Hossana town, southern Ethiopia: A mixed method approach

Authors: Zemzem Jemal, et al. Abstract Backgrounds Worldwide, a substantial proportion of women have low cervical cancer screening services utilization. There is a paucity of evidence in utilization of cervical cancer screening services among female health workers and inconsistent findings in Ethiopia. This study aimed to assess the utilization of cervical cancer screening services and…

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Integrating human papillomavirus testing as a point-of care service using GeneXpert platforms: Findings and lessons from a Kenyan pilot study (2019–2020)

Authors: Valerian Mwenda , et al. Abstract Background Globally, cervical cancer is a major public health problem, with about 604,000 new cases and over 340,000 deaths in 2020. In Kenya, it is the leading cause of cancer deaths, with over 3,000 women dying in 2020 alone. Both the Kenyan cancer screening guidelines and the World…

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