JournalFeeds

Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways

Authors: Yi-Ting Tsai, et al. Citation: Tsai Y-T, Chang C-H, Tsai H-Y (2023) Rege-1 promotes C. elegans survival by modulating IIS and TOR pathways. PLoS Genet 19(8): e1010869. https://doi.org/10.1371/journal.pgen.1010869 Editor: Coleen T. Murphy, Princeton, UNITED STATES Received: November 29, 2022; Accepted: July 12, 2023; Published: August 9, 2023 Copyright: © 2023 Tsai et al. This…

Read More
JournalFeeds

A novel nematode species from the Siberian permafrost shares adaptive mechanisms for cryptobiotic survival with C. elegans dauer larva

Authors: Anastasia Shatilovich , et al. Abstract Some organisms in nature have developed the ability to enter a state of suspended metabolism called cryptobiosis when environmental conditions are unfavorable. This state-transition requires execution of a combination of genetic and biochemical pathways that enable the organism to survive for prolonged periods. Recently, nematode individuals have been…

Read More
JournalFeeds

Matrix prior for data transfer between single cell data types in latent Dirichlet allocation

Authors: Alan Min, et al. Abstract Single cell ATAC-seq (scATAC-seq) enables the mapping of regulatory elements in fine-grained cell types. Despite this advance, analysis of the resulting data is challenging, and large scale scATAC-seq data are difficult to obtain and expensive to generate. This motivates a method to leverage information from previously generated large scale…

Read More