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XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis

Authors: Briana Wilson, et al. Abstract MicroRNAs (miRNAs) are a well-characterized class of small RNAs (sRNAs) that regulate gene expression post-transcriptionally. miRNAs function within a complex milieu of other sRNAs of similar size and abundance, with the best characterized being tRNA fragments or tRFs. The mechanism by which the RNA-induced silencing complex (RISC) selects for…

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Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis

Authors: Xinli Wang, et al. Citation: Wang X, Wei X, Lu Y, Wang Q, Fu R, Wang Y, et al. (2023) Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis. PLoS Biol 21(5): e3002062. https://doi.org/10.1371/journal.pbio.3002062 Academic Editor: Feng Shao, National Institute of Biological Sciences, CHINA Received: July 30, 2022; Accepted:…

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