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Dried Blood Spots (DBS): A suitable alternative to using whole blood samples for diagnostic testing of visceral leishmaniasis in the post-elimination era

Authors: Prakash Ghosh , et al. Abstract Background Serum or whole blood collection, processing, transport and storage still present significant challenges in low resource settings where mass surveillance is required to sustain disease elimination. Therefore, in this study, we explored the diagnostic efficacy of dried blood spots (DBS) as a minimally invasive and potentially cost-effective…

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Endoparasites in dogs diagnosed at the Veterinary Teaching Hospital (VTH)-University of Bologna, combined with clinicopathological results. A long-term retrospective secondary data study

Authors: Benedetto Morandi , et al. Abstract Humans and dogs commonly share the same domestic environment. Europe, and Italy specifically, have a substantial and growing dog population. Potentially zoonotic parasites may be harbored even by dogs receiving regular veterinary care. Thus, transmission of zoonotic or potentially zoonotic parasites to owners and their families should not…

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Microbial thermogenesis is dependent on ATP concentrations and the protein kinases ArcB, GlnL, and YccC

Authors: Puneet Singh Dhatt, et al. Abstract Organisms necessarily release heat energy in their pursuit of survival. This process is known as cellular thermogenesis and is implicated in many processes from cancer metabolism to spontaneous farm fires. However, the molecular basis for this fundamental phenomenon is yet to be elucidated. Here, we show that the…

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Phi fluctuates with surprisal: An empirical pre-study for the synthesis of the free energy principle and integrated information theory

Authors: Christoffer Lundbak Olesen , et al. Citation: Lundbak Olesen C, Waade PT, Albantakis L, Mathys C (2023) Phi fluctuates with surprisal: An empirical pre-study for the synthesis of the free energy principle and integrated information theory. PLoS Comput Biol 19(10): e1011346. https://doi.org/10.1371/journal.pcbi.1011346 Editor: Thomas Parr, University College London Institute of Neurology, UNITED KINGDOM Received:…

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An allelic series at the EDNRB2 locus controls diverse piebalding patterns in the domestic pigeon

Authors: Emily T. Maclary, et al. Citation: Maclary ET, Wauer R, Phillips B, Brown A, Boer EF, Samani AM, et al. (2023) An allelic series at the EDNRB2 locus controls diverse piebalding patterns in the domestic pigeon. PLoS Genet 19(10): e1010880. https://doi.org/10.1371/journal.pgen.1010880 Editor: Gregory S. Barsh, HudsonAlpha Institute for Biotechnology, UNITED STATES Received: July 25,…

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Factors associated with unsuccessful tuberculosis treatment among homeless persons in Brazil: A retrospective cohort study from 2015 to 2020

Authors: Osiyallê Akanni Silva Rodrigues , et al. Abstract Background Tuberculosis (TB) is a preventable and a curable disease. In Brazil, TB treatment outcomes are particularly worse among homeless populations who are either of black race, malnourished or living with HIV/AIDS and other comorbidities. This study therefore evaluated factors associated with unsuccessful TB treatment among…

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Research on coupling control of multiple permanent magnet synchronous motors based on NAISMC and SMDO

Authors: Yunhui Hao , et al. Abstract The synchronous control system of multi-permanent magnet motor has the characteristics of many parameter variables and mutual coupling. The use of sliding mode control to optimize the parameters in the multi-permanent magnet motor system not only ensures the stability of the system operation, but also improves the control…

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A Drosophila glial cell atlas reveals a mismatch between transcriptional and morphological diversity

Authors: Inês Lago-Baldaia, et al. Citation: Lago-Baldaia I, Cooper M, Seroka A, Trivedi C, Powell GT, Wilson SW, et al. (2023) A Drosophila glial cell atlas reveals a mismatch between transcriptional and morphological diversity. PLoS Biol 21(10): e3002328. https://doi.org/10.1371/journal.pbio.3002328 Academic Editor: Cody J. Smith, University of Notre Dame, Center for Stem Cells and Regenerative Medicine,…

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Analyzing histone ChIP-seq data with a bin-based probability of being signal

Authors: Vivian Hecht, et al. Abstract Histone ChIP-seq is one of the primary methods for charting the cellular epigenomic landscape, the components of which play a critical regulatory role in gene expression. Analyzing the activity of regulatory elements across datasets and cell types can be challenging due to shifting peak positions and normalization artifacts resulting…

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The parenting hub of the hypothalamus is a focus of imprinted gene action

Authors: Matthew J. Higgs, et al. Citation: Higgs MJ, Webberley AE, Allan AJ, Talat M, John RM, Isles AR (2023) The parenting hub of the hypothalamus is a focus of imprinted gene action. PLoS Genet 19(10): e1010961. https://doi.org/10.1371/journal.pgen.1010961 Editor: Marisa S. Bartolomei, University of Pennsylvania, UNITED STATES Received: April 19, 2023; Accepted: September 7, 2023;…

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